Mandisa is a South African based women, a public health expert and a qualified clinician with 16 years’ experience in the HIV and TB field. She is an AVAC Alumni- 2020/2021, a U=U pioneer in South Africa, a co-founder of U=U Africa Forum and an author. She obtained MPH, B-Cur degree, Advanced Clinical Management of HIV and Advanced Project Management. She has extensive experience in leading National HIV projects across the cascade and TB research project. She work closely with different United Nations (UN) agencies; Joint United Nations Programme on HIV/AIDS (UNAIDS) and United Nations Population Fund (UNFPA) since 2018 to date. She was nominated by UNAIDS global office to attend a physical meeting held in Brazil in March 2020 to finalise the 2021-2026 Global Aids Targets and formed part of the UNAIDS Expert Group on Integration to the ‘target-setting for 2025. She was invited by UNAIDS Eastern and Southern Africa to a High Level Meeting held in April 2021 discussing strategies to translate the 2021-2026 Global Aids Strategy into regional context and ways in which the 2021-2026 strategy can be aligned to the Sustainable Developmental Goals (SDG’s). She also featured in a number of UNAIDS articles, their website and 2018 annual report. She published a number of HIV articles and presented in different national and international conferences. She was featured in HIV Mag (2021 Amazing people with HIV), Mail and Guardian (Powerful women in 2021), and presented at the WHO HIV Drug resistance report launch.